Submissions from 2016
Non-human Primates in Neuroscience Research: The Case Against its Scientific Necessity, Jarrod Bailey and Katy Taylor
Use of Non-Human Primates in Cocaine Research, Raija H. Bettauer
Alzheimer Disease Research in the 21st Century: Past and Current Failures, New Perspectives and Funding Priorities, Francesca Pistollato, Elan L. Ohayon, Ann Lam, Gillian R. Langley, Thomas J. Novak, David Pamies, George Perry, Eugenia Trushina, Robin S.B. Williams, Alex E. Roher, Thomas Hartung, Stevan Harnad, Neal D. Barnard, Martha Clare Morris, Mei-Chun Lai, Ryan Merkley, and P. Charukeshi Chandrasekera
Submissions from 2015
The Flaws and Human Harms of Animal Experimentation, Aysha Akhtar
A Role for Folk Psychology in Animal Cognition Research, Kristin Andrews
Expectations for Methodology and Translation of Animal Research: A Survey of Health Care Workers, Ari Joffe, Meredith Bara, Natalie Anton, and Nathan Nobis
Lessons from Toxicology: Developing a 21st‑Century Paradigm for Medical Research, Gill Langley, Christopher P. Austin, Anil K. Balapure, Linda S. Birnbaum, John R. Bucher, Julia Fentem, Suzanne C. Fitzpatrick, John R. Fowle III, Robert J. Kavlock, Hiroaki Kitano, Brett A. Lidbury, Alysson R. Muotri, Shuang-Qing Peng, Dmitry Sakharov, Troy Seidle, Thales Trez, Alexander Tonevitsky, Anja van de Stolpe, Maurice Whelan, and Catherine Willett
Submissions from 2014
Anthropomorphism, Anthropectomy, and the Null Hypothesis, Kristin Andrews and Brian Huss
An Analysis of the Use of Animal Models in Predicting Human Toxicology and Drug Safety, Jarrod Bailey, Michelle Thew, and Michael Balls
A Longitudinal View of Primate Life in Two American Laboratories, Jonathan Balcombe
Rethinking the Ethics of Research Involving Nonhuman Animals: Introduction, Tom L. Beauchamp, Hope Ferdowsian, and John P. Gluck
The Usefulness of Systematic Reviews of Animal Experiments for the Design of Preclinical and Clinical Studies, Rob B.M. de Vries, Kimberley E. Weaver, Marc T. Avey, Martin Stephens, Emily S. Sena, and Marlies Leenaars
Moving Beyond the Welfare Standard of Psychological Well-Being for Nonhuman Primates: The Case of Chimpanzees, John P. Gluck
The Ethics of Animal Research: A Survey of Pediatric Health Care Workers, Ari Joffe, Meredith Bara, Natalie Anton, and Nathan Nobis
Considering a New Paradigm for Alzheimer’s Disease Research, Gillian R. Langley
Consensus Report on the Future of Animal-Free Systemic Toxicity Testing, Marcel Leist, Nina Hasiwa, Costanza Rovida, Mardas Daneshian, David Basketter, Ian Kimber, Harvey Clewell, Tilman Gocht, Alan Goldberg, Francois Busquet, Anna-Maria Rossi, Michael Schwarz, Martin Stephens, Rob Taalman, Thomas B. Knudsen, James McKim, Georgina Harris, David Pamies, and Thomas Hartung
Defining and Assessing Animal Pain, Lynne U. Sneddon, Robert W. Elwood, Shelley A. Adamo, and Matthew C. Leach
Submissions from 2013
Prolonged Pain Research in Mice: Trends in Reference to the 3Rs, Jonathan Balcombe, Hope Ferdowsian, and Lauren Briese
Food for Thought … Mechanistic Validation, Thomas Hartung, Sebastian Hoffman, and Martin Stephens
Can Acute Dermal Systemic Toxicity Tests Be Replaced With Oral Tests? A Comparison of Route-Specific Systemic Toxicity and Hazard Classifications Under the Globally Harmonized System of Classification and Labelling of Chemicals (GHS), Nigel P. Moore, David J. Andrew, Donald L. Bjerke, Stuart Creton, David Dreher, Thomas Holmes, Pilar Prieto, Troy Seidle, and Tim G. Rowan
Humane Society International’s Global Campaign to End Animal Testing, Troy Seidle
Submissions from 2012
The Moral Status of Invasive Animal Research, Bernard E. Rollin
Pursuing Medawar’s Challenge for Full Replacement, Martin Stephens
Submissions from 2011
Systematic Review of Chimpanzee Use in Monoclonal Antibody Research and Drug Development: 1981-2010, Raija Bettauer
Harnessing Opportunities in Non-Animal Asthma Research for a 21st-Century Science, Gemma L. Buckland
Ethical and Scientific Considerations Regarding Animal Testing and Research, Hope Ferdowsian and Nancy Beck
A Kenyan Perspective on the Use of Animals in Science Education and Scientific Research in Africa and Prospects for Improvement, Charles Kimwele, Duncan Matheka, and Hope Ferdowsian
Assessing the Necessity of Chimpanzee Experimentation, Andrew Knight
Towards a New Paradigm of Non-Captive Research on Cetacean Cognition, Lori Marino and Toni Frohoff
The Harmful, Nontherapeutic Use of Animals in Research Is Morally Wrong, Nathan Nobis
Examining the Regulatory Value of Multi-Route Mammalian Acute Systemic Toxicity Studies, Troy Seidle, Pilar Prieto, and Anna Bulgheroni
Submissions from 2010
The Current Scientific and Legal Status of Alternative Methods to the LD50 Test for Botulinum Neurotoxin Potency Testing, Sarah Adler, Gerd Bicker, Hans Bigalke, Christopher Bishop, Jörg Blümel, Dirk Dressler, Joan Fitzgerald, Frank Gessler, Heide Heuschen, Birgit Kegel, Andreas Luch, Catherine Milne, Andrew Pickett, Heidemarie Ratsch, Irmela Ruhdel, Dorothea Sesardic, Martin Stephens, Gerhard Stiens, Peter D. Thornton, René Thürmer, Martin Vey, Horst Spielmann, Barbara Grune, and Manfred Liebsch
An Assessment of the Use of Chimpanzees in Hepatitis C Research Past, Present and Future: 1. Validity of the Chimpanzee Model, Jarrod Bailey
An Assessment of the Use of Chimpanzees in Hepatitis C Research Past, Present and Future: 2. Alternative Replacement Methods, Jarrod Bailey
Toxicity Testing in the 21st Century: A Vision and a Strategy, Daniel Krewski, Daniel Acosta Jr, Melvin Anderson, Henry Anderson, John C. Bailar III, Kim Boekelheide, Robert Brent, Gail Charnley, Vivian G. Cheung, Sidney Green Jr, Karl T. Kelsey, Nancy I. Kerkvliet, Abby A. Li, Lawrence McCray, Otto Meyer, Reid D. Patterson, William Pennie, Robert A. Scala, Gina M. Solomon, Martin Stephens, James Yager, and Lauren Zeise
Cross-Sector Review of Drivers and Available 3Rs Approaches for Acute Systemic Toxicity Testing, Troy Seidle, Sally Robinson, Tom Holmes, Stuart Creton, Pilar Prieto, Julia Scheel, and Magda Chlebus
A Modular One-Generation Reproduction Study as a Flexible Testing System for Regulatory Safety Assessment, Richard Vogel, Troy Seidle, and Horst Spielmann
Submissions from 2009
The SCHER Report on Non-human Primate Research — Biased and Deeply Flawed, Jarrod Bailey and Katy Taylor
Addressing Distress and Pain in Animal Research: The Veterinary, Research, Societal, Regulatory and Ethical Contexts for Moving Forward, Kathleen Conlee, Martin Stephens, and Andrew N. Rowan
The Validity of Animal Experiments in Medical Research, Gill Langley
Interests and Harms in Primate Research, Nathan Nobis
Scientific Autonomy and the 3Rs, Bernard E. Rollin
Bringing Toxicology into the 21st Century: A Global Call to Action, Troy Seidle and Martin Stephens
Submissions from 2008
Developmental Toxicity Testing: Protecting Future Generations?, Jarrod Bailey
Non-Animal Methodologies within Biomedical Research and Toxicity Testing, Andrew Knight
Reviewing Existing Knowledge Prior to Conducting Animal Studies, Andrew Knight
Systematic Reviews of Animal Experiments Demonstrate Poor Contributions to Human Healthcare, Andrew Knight
The Beginning of the End for Chimpanzee Experiments?, Andrew Knight
Volunteer Studies in Pain Research — Opportunities and Challenges to Replace Animal Experiments: The Report and Recommendations of a Focus on Alternatives Workshop, C. K. Langley, Q. Aziz, C. Bountra, N. Gordon, P. Hawkins, A. Jones, G. Langley, T. Nurmikko, and I. Tracey
Submissions from 2007
Chimpanzee Research: An Examination of Its Contribution to Biomedical Knowledge and Efficacy in Combating Human Diseases, Jarrod Bailey, Jonathan Balcombe, and Theodora Capaldo
The Development of New Concepts for Assessing Reproductive Toxicity Applicable to Large Scale Toxicological Programmes, S. Bremer, C. Pellizzer, S. Hoffmann, T. Seidle, and T. Hartung
Systematic Reviews of Animal Experiments Demonstrate Poor Human Clinical and Toxicological Utility, Andrew Knight
The Poor Contribution of Chimpanzee Experiments to Biomedical Progress, Andrew Knight
Animal Research: A Moral Science, Bernard E. Rollin
Of Mice and Men, Bernard E. Rollin
Overcoming Ideology: Why It Is Necessary to Create a Culture in Which the Ethical Review of Protocols Can Flourish, Bernard E. Rollin
A Holistic Approach to Taking Research Animal Suffering Seriously, Martin Stephens and Kathleen Conlee
Submissions from 2006
Animal Carcinogenicity Studies: 1. Poor Human Predictivity, Andrew Knight, Jarrod Bailey, and Jonathan Balcombe
Animal Carcinogenicity Studies: 2. Obstacles to Extrapolation of Data to Humans, Andrew Knight, Jarrod Bailey, and Jonathan Balcombe
Animal Carcinogenicity Studies: 3. Alternatives to the Bioassay, Andrew Knight, Jarrod Bailey, and Jonathan Balcombe
Animal Carcinogenicity Studies: Implications for the REACH System, Andrew Knight, Jarrod Bailey, and Jonathan Balcombe
Cancerous Contradictions: The Mis-Regulation of Human Carcinogens Based on Animal Data, Andrew Knight, Jarrod Bailey, and Jonathan Balcombe
Submissions from 2005
The Future of Teratology Research is In Vitro, Jarrod Bailey, Andrew Knight, and Jonathan Balcombe
127 Million Non-human Vertebrates Used Worldwide for Scientific Purposes in 2005, Andrew Knight
Which Drugs Cause Cancer?, Andrew Knight, Jarrod Bailey, and Jonathan Balcombe
Ethics of Critical Care, Bernard E. Rollin
LD50 Testing of Botulinum Toxin for Use as a Cosmetic, Martin L. Stephens and Michael Balls
Submissions from 2004
Medical Training Using Simulation: Toward Fewer Animals and Safer Patients, Jonathan Balcombe
Levels of Citation of Nonhuman Animal Studies Conducted at a Canadian Research Hospital, Anne Innis Dagg and Troy K. Seidle
Animals and Alternatives: Societal Expectations and Scientific Need, Alan M. Goldberg
An Evaluation of the US High Production Volume (HPV) Chemical-testing Programme: A Study in (Ir)Relevance, Redundancy and Retro Thinking, Andrew Nicholson, Jessica Sandler, and Troy Seidle
Ideology Masquerading as Science: The Case of Endocrine Disrupter Screening Programmes, Troy Seidle
Animal Model Research: The Apples and Oranges Quandary, Kenneth J. Shapiro
Submissions from 2003
Ethical Issues in the Use of Animals in Biomedical and Psychopharmocological Research, John P. Gluck and Jordan Bell
Toxicology and New Social Ethics for Animals, Bernard E. Rollin
What it is to be a Dog: A Qualitative Method for the Study of Animals Other than Humans, Kenneth J. Shapiro
Submissions from 2002
Possibilities for Refinement and Reduction: Future Improvements Within Regulatory Testing, Martin L. Stephens, Kathleen Conlee, Gina Alvino, and Andrew N. Rowan
Submissions from 2001
The Ethical Limits of Domestication: A Critique of Henry Heffner’s Arguments, Colin Allen, Marc Bekoff, and Lori Gruen
Dissection: The Scientific Case for Alternatives, Jonathan Balcombe
Submissions from 1998
Psychology's Use of Animals: Current Practices and Attitudes, Kenneth J. Shapiro
Unrelieved Pain and Distress in Animals: An Analysis of USDA Data on Experimental Procedures, Martin Stephens, Philip Mendoza, Adrianna Weaver, and Tamara Hamilton
Submissions from 1997
Harry F. Harlow and Animal Research: Reflection on the Ethical Paradox, John P. Gluck
Submissions from 1996
Gender Differences in Attitudes Toward Animal Research, Jennifer J. Eldridge and John P. Gluck
A Rodent for your Thoughts: The Animal Model Strategy in Psychology, Kenneth J. Shapiro
The Ingrown World of Animal Model Research in Psychology, Kenneth J. Shapiro
Submissions from 1995
The Three Rs: The Way Forward, Michael Balls, Alan M. Goldberg, Julia H. Fentem, Caren L. Broadhead, Rex L. Burch, Michael F.W. Festing, John M. Frazier, Coenraad F.M. Hendriksen, Margaret Jennings, Margot D.O. van der Kamp, David B. Morton, Andrew N. Rowan, Claire Russell, William M.S. Russell, Horst Spielmann, Martin Stephens, William S. Stokes, Donald W. Straughan, James D. Yager, Joanne Zurlo, and Bert F.M. van Zutphen
Scientists and Animal Research: Dr. Jekyll or Mr. Hyde?, Andrew N. Rowan
The Animal Research Controversy: Protest, Process & Public Policy, Andrew N. Rowan, Franklin M. Loew, and Joan C. Weer
How the Rat Turned White, Kenneth J. Shapiro
Submissions from 1994
Animal Protection and Medical Science, David O. Wiebers, Jennifer Leaning, and Roger D. White
Submissions from 1992
The Ethical Judgment of Animal Research, Shelley L. Galvin and Harold A. Herzog
Submissions from 1991
Animals in Biomedical Research: The Undermining Effect of the Rhetoric of the Besieged, John P. Gluck and Steven R. Kubacki
Use Morality as Basis for Animal Treatment, Kenneth J. Shapiro
Submissions from 1990
Alternatives to and Reduction of Animal Use in Biomedical Research, Education and Testing, John M. Frazier and Alan M. Goldberg
Long-Term Effects of Early Social Isolation in Macaca mulatta: Changes in Dopamine Receptor Function Following Apomorphine Challenge, Mark H. Lewis, John P. Gluck, Tom L. Beauchamp, Michael F. Keresztury, and Richard B. Mailman
Submissions from 1988
A New Invasiveness Scale: Its Role in Reducing Animal Distress, Kenneth J. Shapiro and Peter B. Field
Submissions from 1986
Ethics, Welfare, and Laboratory Animal Management, David J. Allan and Judith K. Blackshaw
