Submissions from 2019
Beyond the 3Rs: Expanding the Use of Human-Relevant Replacement Methods in Biomedical Research, Kathrin Herrmann, Francesca Pistollato, and Martin L. Stephens
Submissions from 2017
Considering aspects of the 3Rs principles within experimental animal biology, Lynne U. Sneddon, Lewis G. Halsey, and Nic R. Bury
Submissions from 2016
Alzheimer Disease Research in the 21st Century: Past and Current Failures, New Perspectives and Funding Priorities, Francesca Pistollato, Elan L. Ohayon, Ann Lam, Gillian R. Langley, Thomas J. Novak, David Pamies, George Perry, Eugenia Trushina, Robin S.B. Williams, Alex E. Roher, Thomas Hartung, Stevan Harnad, Neal D. Barnard, Martha Clare Morris, Mei-Chun Lai, Ryan Merkley, and P. Charukeshi Chandrasekera
Submissions from 2015
The multifactorial role of the 3Rs in shifting the harm-benefit analysis in animal models of disease, Melanie L. Graham and Mark J. Prescott
Lessons from Toxicology: Developing a 21st‑Century Paradigm for Medical Research, Gill Langley, Christopher P. Austin, Anil K. Balapure, Linda S. Birnbaum, John R. Bucher, Julia Fentem, Suzanne C. Fitzpatrick, John R. Fowle III, Robert J. Kavlock, Hiroaki Kitano, Brett A. Lidbury, Alysson R. Muotri, Shuang-Qing Peng, Dmitry Sakharov, Troy Seidle, Thales Trez, Alexander Tonevitsky, Anja van de Stolpe, Maurice Whelan, and Catherine Willett
Submissions from 2014
Considering a New Paradigm for Alzheimer’s Disease Research, Gillian R. Langley
Consensus Report on the Future of Animal-Free Systemic Toxicity Testing, Marcel Leist, Nina Hasiwa, Costanza Rovida, Mardas Daneshian, David Basketter, Ian Kimber, Harvey Clewell, Tilman Gocht, Alan Goldberg, Francois Busquet, Anna-Maria Rossi, Michael Schwarz, Martin Stephens, Rob Taalman, Thomas B. Knudsen, James McKim, Georgina Harris, David Pamies, and Thomas Hartung
Submissions from 2012
A Roadmap for the Development of Alternative (Non-Animal) Methods for Systemic Toxicity Testing, David Basketter, Harvey Clewell, Ian Kimber, Annamaria Rossi, Bas Blaauboer, Robert Burrier, Mardas Daneshian, Chantra Eskes, Alan Goldberg, Nina Hasiwa, Sebastian Hoffmann, Joanna Jaworska, Thomas B. Knudsen, Robert Landsiedel, Marcel Leist, Paul Locke, Gavin Maxwell, James McKim, Emily McVey, Gladys Ouédraogo, Grace Patlewicz, Olavi Pelkonen, Erwin Roggen, Costanza Rovida, Irmela Ruhdel, Michael Schwarz, Andreas Schepky, Greet Schoeters, Nigel Skinner, Kerstin Trentz, Marian Turner, Philippe Vanparys, James Yager, Joanne Zurlo, and Thomas Hartung
Alternative Approaches for Medical Countermeasures to Biological and Chemical Terrorism and Warfare, Thomas Hartung and Joanne Zurlo
Pursuing Medawar’s Challenge for Full Replacement, Martin Stephens
Submissions from 2011
Harnessing Opportunities in Non-Animal Asthma Research for a 21st-Century Science, Gemma L. Buckland
Submissions from 2010
Toxicity Testing in the 21st Century: A Vision and a Strategy, Daniel Krewski, Daniel Acosta Jr, Melvin Anderson, Henry Anderson, John C. Bailar III, Kim Boekelheide, Robert Brent, Gail Charnley, Vivian G. Cheung, Sidney Green Jr, Karl T. Kelsey, Nancy I. Kerkvliet, Abby A. Li, Lawrence McCray, Otto Meyer, Reid D. Patterson, William Pennie, Robert A. Scala, Gina M. Solomon, Martin Stephens, James Yager, and Lauren Zeise
Submissions from 2008
Non-Animal Methodologies within Biomedical Research and Toxicity Testing, Andrew Knight
Submissions from 2007
The Development of New Concepts for Assessing Reproductive Toxicity Applicable to Large Scale Toxicological Programmes, S. Bremer, C. Pellizzer, S. Hoffmann, T. Seidle, and T. Hartung
Submissions from 2004
Ideology Masquerading as Science: The Case of Endocrine Disrupter Screening Programmes, Troy Seidle
Submissions from 2002
Possibilities for Refinement and Reduction: Future Improvements Within Regulatory Testing, Martin L. Stephens, Kathleen Conlee, Gina Alvino, and Andrew N. Rowan
Submissions from 1985
The Imbalance Between Experiment and Theory in Biology: The Need for Theory-Directed Modeling, M. L. Fidelman and D. C. Mikulecky
Submissions from 1979
Alternatives to Laboratory Animals: Definition and Discussion, Andrew N. Rowan